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Breast cancer biomarker technologies
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Structure and biology of a carcinoma-associated mucin, MUC1. The New England Journal of Medicine. Sznol M, Chen L. To date, there are many reports on the potential biomarkers for various types of cancer. Three-dimensional 3D cell culture models Traditionally, cell-based assays to explore cell biology and drug efficacy have been aimed at growing cells on two-dimensional 2D plastic surfaces or in single cell suspensions [ ].



Notable examples of potentially predictive cancer biomarkers include mutations on genes KRAS, p53, EGFR, erbB2 for colorectal, esophageal, liver, and pancreatic cancer; mutations of genes BRCA1 and BRCA2 for breast and ovarian cancer; abnormal methylation of tumor suppressor genes p16, CDKN2B, and p14ARF for brain cancer; hypermethylation of MYOD1, CDH1, and CDH13 for cervical cancer; and hypermethylation of p16, p14, and RB1, for oral cancer. A biomarker is defined by the National Cancer Institute as "a biological molecule found in the blood, other bodily fluids or tissue that is a sign of normal or abnormal process, or of a condition or disease." Biomarkers may be produced by both normal cells and cancer cells, but are often up-regulated or misregulated in cancer. Jan 15,  · Biomarker Technologies LLC develops diagnostic tests to detect breast cancer. The company offers BT Test, a blood diagnostic test that detects the presence of breast cancer Location: East Arizona Biltmore Circle Suite Phoenix, AZ United States.




Until superior therapeutic treatments are developed to prevent, treat and cure cancer, the best means of reducing mortality and morbidity in a disease this complex is early detection and diagnosis. In the major solid cancer types such as lung, breast, colon and prostate, long-term survival rates drop precipitously once metastatis has occurred. The case is clear for development of biomarkers for early detection and screening tests for breast cancer biomarker technologies such as breast, colon, ovarian and lung cancer. Breast cancer biomarker technologies addition, diagnostic measurement of cancer disease progression is essential to successful disease management. For these reasons, development of new and effective biomarkers for cancer detection and diagnosis is central to the cancer problem.

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Breast cancer biomarker technologies
Breast cancer biomarker technologies
Breast cancer biomarker technologies
Breast cancer biomarker technologies

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Yozshugul 10 months ago
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Breast cancer biomarker technologies

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