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Of the cytokines participating in the cancer process, interleukin 6 IL-6 has been shown to promote breast cancer metastasis [ 16 — 18 ], and high IL-6 levels are associated with poor clinical outcomes in breast tumors [ 19 ]. We conclude that YB1 is capable of repressing transcription of the p53 promoter in vitro. A driver of tumorigenesis. Associations have also been reported between EZH2 overexpression and poor prognosis in esophageal cancers [8], breast cancers [9], renal cell carcinomas [10] and childhood intracranial ependymoma [11]. The biological characteristics of both eutopic and ectopic endometrial tissues as well as their clinical correlations with the disease are highlighted, with the primary objective of understanding the role of the eutopic endometrium in this enigmatic gynecological disorder. An inverse relationship between YB-1 and E-cadherin levels has been reported in many cancer cell lines and breast tumors [ 29 , 32 , 33 , 47 ].






Mouse over the terms for more detail; many indicate links which you can click for dedicated pages about the topic. Data table showing topics related to specific cancers and associated disorders. Scope includes mutations yb1 breast colorectal cancer abnormal protein expression. Number of papers are based on searches of PubMed click on topic title for arbitrary criteria used. Summary of gene and mutations by cancer type from ICGC.

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